ea0007p41 | Diabetes, metabolism and cardiovascular | BES2004
Syed A
, Irving J
, Redfern C
, Hall A
, Unwin N
, White M
, Bhopal R
, Alberti K
, Weaver J
Some people with obesity have hormonal, metabolic and circulatory changes that constitute the metabolic syndrome that resemble characteristics of patients with Cushing's syndrome. A link between the two conditions, possibly genetic, has therefore been suspected, and the glucocorticoid receptor gene (GRL, 5q31-q32) has been one of the candidate genes.The single nucleotide polymorphism N363S is an ATT to GTT missense alteration within exon 2 of G...